Real-world study finds patients switching from obesity shots to Novo’s daily Wegovy pill lose 4.1% in three months
Real-world data presented at EASD suggests patients switching from injectable obesity therapies to Novo's oral semaglutide (Wegovy pill) achieved meaningful short-term weight loss and improved obesity classification, supporting adherence and efficacy concerns around pills. With oral therapies rising to roughly a third of U.S. obesity prescriptions and Novo capturing most new oral starts, the findings strengthen Novo's positioning versus Lilly in the fast-growing GLP-1 market.
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A real-world study found patients who moved from injectable obesity treatments to a daily oral semaglutide pill lost an average of 4.1% of body weight over three months, or 4.0 kg, from a 221.6-pound baseline. The share classified as clinically obese fell to 65.5% from 87.1% over the same period. Nearly 41% of participants lost at least 5% of their body weight. The findings were presented at a medical conference as Novo Nordisk pushes an oral obesity option amid competition from Eli Lilly.